— 01 / 1st
1st
Hyaluronic Acid
Water Glow Injection
Injecting hyaluronic acid into the dermis to supplement moisture. Focused on simple hydration and moisture improvement.
Skin to
Skin.Re2O
Elravie Re2OA way to restore the materials time has taken from the dermis. Not sending signals to produce collagen, but a new approach that replenishes the dermis itself.
Scroll · Explore
§ 01 · What is ECM · Extracellular Matrix
Restoring the lost
materials of the dermis
It's not just collagen that decreases with age. The entire scaffold surrounding it — ECM (Extracellular Matrix) — collapses together. When elastin breaks, GAG depletes, and dermal density thins out, we call it 'aging'.
Re2O restores human-derived dermal tissue (hADM) to fill the gap. Not a detour that stimulates collagen production, but a direct path that replenishes the building materials of the collapsed structure.
hADM
Collagen 89%
Elastin 3%
GAG 0.4%
AATB · FDA · MFDS
Depth
00%
§ 02 · 3-Step Remodeling · ECM Delivery
ECM
penetrates
into the skin
When hADM particles are injected into the dermis, the skin environment is fundamentally improved through a systematic 3-step process: immediate reinforcement → fibroblast activation → long-term remodeling.
When fine ECM particles settle in the dermis, they interact with surrounding fibroblasts to form an ECM network. Not induction, but direct replenishment.
01
Immediate Reinforcement
02
Cell Activation
03
Long-term Remodeling
— Step 01 · Immediate Reinforcement
Epidermis Passage Zone
Dermis ECM Settlement Zone
Hypodermis Subcutaneous Tissue
§ 03 · Evolution
From induction to
direct replenishment
The history of skin boosters has been a journey of 'how to revive collagen.' Re2O changes the question itself — why only replenish collagen?
— 02 / 2nd
2nd
Rejuran
PN Booster
Stimulating fibroblasts with polynucleotide (PN) to induce collagen production.
— 03 / 3rd
3rd
Juvelook
PDLLA
Stimulating collagen synthesis using a micro foreign body reaction.
— 04 / 4th
4th
Re2O
ECM Booster
Directly replenishing human-derived ECM to restore the dermal structure itself. Direct supply, not induction.
World's First ECM Booster§ 04 · Clinical Data
One Treatment,
10 Changes
Based on clinical trial data 1 month after Re2O+HA combined treatment. Comprehensive skin improvement confirmed with a single treatment.
Pore Reduction
Skin Radiance
Deep Hydration
Elasticity & Regeneration
Texture Improvement
Dark Spots & Blemishes
Fine Line Reduction
Redness Reduction
Skin Barrier
Roughness Improvement
§ 05 · Line-up
One Material,
Two Densities
Original for broad-area structural restoration, Fine for delicate area texture refinement. Choose by purpose.
| Category | Re2O Original | Re2O Fine |
|---|---|---|
| Particle Size | Standard particles | Approx. 50μm fine particles |
| Features | Rich ECM replenishment Focus on dermal structure restoration | Precise injection with fine particles Detailed treatment for sensitive areas |
| Application Areas | Forehead, cheeks, jawline — broad areas | Around eyes, neck, lips — delicate areas |
| Recommended For | Overall elasticity & regeneration Volume improvement | Subtle texture & tone refinement Focused care for sensitive areas |
Replenishing
your skin with
its true essence
It's not about signaling for more collagen; it's about restoring the dermis itself. Re2O replenishes the ECM that time has taken away.